Homepage | Archives of Disease in Childhood
WEB2 days ago · Archives of Disease in Childhood (ADC) is an international and peer-reviewed journal specialising in child health, covering the perinatal period through to adolescence. As an official journal of the Royal College of Paediatrics and Child Health, ADC provides paediatricians with the most recent, relevant and original research reports ...
Current evidence-based recommendations on investigating …
WEBIntroduction Global developmental delay (GDD) affects 1%–3% of the population of children under 5 years of age, making it one of the most common conditions presenting in paediatric clinics; causes are exogenous, genetic (non-metabolic) or genetic (metabolic). Recent advances in biotechnology and genetic testing mean that the investigations available to perform for children under 5 years are ...
Cardiovascular effects of mechanical ventilation
WEBThe influence of ventilation on cardiac function. Spontaneous and mechanical ventilation induce changes in intrapleural or intrathoracic pressure and lung volume, which can independently affect the key determinants of cardiovascular performance: atrial filling or preload; the impedance to ventricular emptying or …
Role of diagnostic tests for sepsis in children: a review
WEBPaediatric sepsis has a significant global impact and highly heterogeneous clinical presentation. The clinical pathway encompasses recognition, escalation and de-escalation. In each aspect, diagnostics have a fundamental influence over outcomes in children. Biomarkers can aid in creating a larger low-risk group of children from those in the clinical grey area who would otherwise receive ...
Table of contents | Archives of Disease in Childhood
WEBAug 18, 2022 · Vivek Mundada, Pawankumar Maniyar. Images in paediatrics: Strabismus in juvenile hyperthyroidism: not just thyroid-associated ophthalmopathy (25 February, 2022) Xin Wei, Xin Qi. Archivist: After the FEAST study (18 August, 2022) Images in paediatrics: Presternal swelling: remember mumps (25 April, 2022) Roberta-Celine Ellul, …
About - Archives of Disease in Childhood
WEBThe content of Archives of Disease in Childhood is endorsed by the Royal College of Paediatrics and Child Health for Continued Professional Development in line with RCPCH CPD guidelines. Archives of Disease in Childhood is the flagship of BMJ’s paediatrics portfolio and has an open access companion journal, BMJ Paediatrics Open.For information about the Editor-in-Chief and editorial team ...
Diagnosis and management of benign intracranial hypertension
WEBBenign intracranial hypertension (BIH) is a headache syndrome characterised by (1) raised cerebrospinal fluid (CSF) pressure in the absence of an intracranial mass lesion or ventricular dilatation; (2) normal spinal fluid composition; (3) usually normal findings on neurological examination except for papilloedema and an occasional VI nerve palsy; and (4) normal level of consciousness. The ...
Prescribing for children - Archives of Disease in Childhood
WEBThe taste of an antibiotic is often not taken into account by practitioners, although there is significant evidence to show palatability correlates strongly with adherence. Many parents will be familiar with the difficulties of convincing young children to take bitter, unfamiliar medicine. Certain drugs, for example flucloxacillin, are so unpalatable that they should not be prescribed as ...
Varicella vaccination—a critical review of the evidence
WEBVaricella (chickenpox) is an universal, highly infectious disease characterised by a pruritic vesicular eruption associated with fever and malaise caused by varicella zoster virus (VZV). In children, the illness is usually self limiting, lasting four to five days, but at least 1% of children under 15 years experience a complication.1 ,2 These include secondary bacterial infection (particularly ...
O24 Ivermectin in children: what is the right dose to achieve ...
WEBResults Clearance per kilogram was higher in children than in adults, with a median (90% confidence interval) of 0.35 (0.12–0.73) L/h/kg in children compared to 0.20 (0.10–0.31) L/h/kg in adults. As a result, ivermectin exposure in children following a 200 µg/kg dose is ∼30% lower than in adults. An increased dose of 250 and 300 µg/kg would be needed in school-aged children (6–12 ...