Khmelnytskyi is a city in western Ukraine. Located on the Southern Bug, it serves as the administrative centre of Khmelnytskyi Oblast as well a…Khmelnytskyi is a city in western Ukraine. Located on the Southern Bug, it serves as the administrative centre of Khmelnytskyi Oblast as well as Khmelnytskyi Raion within the oblast. With a population of 274,452, Khmelnytskyi is the second-largest city in the historical region of Podolia, after Vinnytsia.