Production tips from Crystal Bio, TriLink Biotechnologies, Ginkgo Bioworks, Quantoom Biosciences, and Parexel.

At its so-called 3' end, mRNA is equipped with a polyadenine tail with an average length of 200 nucleotides. But even this shield does not last long—the average half-life of mRNA is only seven ...

At its so-called 3' end mRNA is equipped with a polyadenine tail with an average length of 200 nucleotides. But even this shield does not last long -- the average half-life of mRNA is only 7 hours.

Use precise geolocation data and actively scan device characteristics for identification. This is done to store and access ...

Nanoparticles have once again reached the spotlight, this time as a critical tool to combat the spread of covid-19. In this ...

Crispr has already secured a historic first approval for a CRISPR/Cas9 drug and has several more potential blockbuster ...

The mRNAs are formulated in novel patented lipid nanoparticles, which prolong the half-life of the mRNA and deliver it to immunoactive antigen-presenting cells, which enhances T-cell responses.

Discover how next-generation "switchable" CAR-T cells could improve both the safety and efficacy of CAR-T therapies.

(2) In Figure 7, the direct binding between YTHDF2 and the potential target genes should be further validated by silencing YTHDF2 to observe the half-life of the mRNA levels of target genes, in ...

It performs two main functions: first, it extends effective half-life of LNPs in the bloodstream by diminishing ... the progress of improvements in LNP-based systems of delivery of mRNA owing to ...