The Lions-Vikings finale will also feature the most combined wins in a regular-season game in NFL history, per Elias Sports.

SAN FRANCISCO (WNEM) - The Detroit Lions are in San Francisco to take on the 49ers for Monday Night Football. Kickoff is set for 8:15 p.m. The Lions are still fighting for the No. 1 seed in the NFC, ...

Use BetMGM bonus code SDS1500 to begin with a wager up to $1,500 on the Lions vs. 49ers or College Football Playoff.

You can listen to the 49ers vs. Lions live on SiriusXM. Coverage will be available on channels 225 (49ers) and 226 (Lions).

LeBron James, in his next game, will become the first player in NBA history to play in his teens, 20s, 30s and 40s.

NFL Week 17 closes with Monday Night Football as the Detroit Lions visit the San Francisco 49ers. Start time, where to stream ...

The Lions (13-2) are looking to continue their winning ways against the 49ers (6-9) and keep their spot at the top of the NFC ...

Here are the two critical matchups to watch on MNF between Detroit Lions and San Francisco 49ers in Week 17, including Penei Sewell against Nick Bosa.

The Lions and 49ers kick off tonight at 5:15 p.m. PT (8:15 p.m. ET) on ABC, ESPN and ESPN Plus. Looking for the ManningCast?

If the Lions beat San Francisco on Monday night, it’ll officially mark the first time in NFL history that a 14-win team is ...

The Week 17 edition of Monday Night Football may not mean much for either the San Francisco 49ers or Detroit Lions, but it means plenty for bettors and fantasy ...