Rookie Malik Mustapha has stepped into a starting role nicely after veteran Talanoa Hufanga went down with a wrist injury.

While he is still officially listed as "questionable" for Sunday, it appears San Francisco 49ers All-Pro running back ...

The San Francisco 49ers are officially gearing up for the return of running back Christian McCaffrey. While they haven’t ...

San Francisco 49ers star Christian McCaffrey discussed the Achilles issue that forced him to miss the first eight games of ...

Spending the first half of the season as a spectator while he worked his way back from Achilles tendinitis took its toll on ...

A transcription of what McCaffrey had to say the 49ers (4-4) departed to face the Tampa Bay Buccaneers (4-5) Sunday: Q: Can ...

What to look for from the top 49ers and Buccaneers players and how to watch the game as they face off on Sunday, week 10.

San Francisco 49ers head coach Kyle Shanahan told KNBR on Thursday that he expects all-everything running back Christian ...

the Titans. … And this will be a week of regression for Pittsburgh QB Russell Wilson against the Commanders. San Francisco ...

NFL Week 10 odds, picks, predictions, TV and streaming information for Sunday football game between San Francisco 49ers and ...

The San Francisco 49ers are road favorites of around 6 points at the injury-plagued Tampa Bay Buccaneers, with the total set ...